Alcohol and liver cell necrosis
نویسندگان
چکیده
منابع مشابه
Alcohol Disrupts Human Liver Stem/Progenitor Cell Proliferation and Differentiation
OBJECTIVE Excessive alcohol consumption injures the liver resulting in various liver diseases including liver cirrhosis. Advanced liver disease continues to be a major challenge to human health. Liver stem/progenitor cells (LSPCs) are tissue specific precursors with a distinct capacity of multi-lineage differentiation. These precursor cells may play an important role in the process of tissue in...
متن کاملAlcohol and liver damage
Chronic heavy drinking can cause the liver to become fatty. Fat deposits in the liver block the liver cells from their blood supply, depriving them of oxygen and other nutrients, eventually killing them. As the name implies, the liver performs so many vital functions that we cannot live without it. The liver filters all of the blood in our bodies, breaking down and eliminating toxins, convertin...
متن کاملAlcohol and liver damage.
The association of aicohol with cirrhosis was recognised by~vfatthew Ba-ilhe4& 1793 and later by Addison. In Western countries the incidence of cirrhosis canbe directly related to the quantity of aicohol consumed. In France, between—1941 and 1947, rationing of wine from five to one litre per week led to an 80% reduction in mortaiity from cirrhosis (1). Cirrhosis is on the increase. In the U.S.A...
متن کاملEffects of Inflammatory Cytokine Tumor Necrosis Factor-α on Human Mesenchymal Stem Cell Gene Expression: A Mechanism for Liver Regeneration
Introduction Insulin-like growth factor I (IGF-I) which is produced in abundance in the normal adult liver, is deeply involved in hepatocyte survival, growth, and differentiation during liver development. IGF-I plays the roles via the receptor (IGF-IR) signaling pathway. IGF-IR unlike IGF-I is expressed strongly in the developing liver, but much more weakly in adults. Objective: We hypothesi...
متن کاملExperimental Liver Necrosis
The results outlined in this communication constitute a partial report of a somewhat comprehensive investigation s now in progress of the chemical processes concerned in the variations occurring in the amounts of fats and lipoids in the hepatic cell under normal and various pathological conditions. It has seemed advisable, in connection with the other investigations of liver necrosis here prese...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1981
ISSN: 0016-5085
DOI: 10.1016/0016-5085(81)90624-7